![[Defunct]](figures/lifecycle-defunct.svg)
Writes a combined exclusions file including UKB recommended exclusions, heterozygosity exclusions (+/- 3*sd from mean), genetic ethnicity exclusions (based on the UKB genetic ethnic grouping variable, field 1002), and relatedness exclusions (a randomly-selected member of each related pair). For exclusion of individuals from a genetic analysis, the PLINK flag --remove accepts a space/tab-delimited text file with family IDs in the first column and within-family IDs in the second column (i.e., FID IID), without a header.
ukb_gen_write_plink_excl(path)Arguments
- path
A path to a file.
See also
ukb_gen_meta, ukb_gen_pcs which retrieve variables to be included in a covariate file. ukb_gen_excl_to_na to update a phenotype with NAs for samples to-be-excluded based on genetic metadata, and ukb_gen_write_plink and ukb_gen_write_bgenie
Examples
if (FALSE) {
# Supply name of a file to write PLINK format combined exclusions
ukb_gen_write_plink_excl("combined_exclusions.txt")
}